Gabapentin

Gabapentin

가바펜틴

중추신경계

60142-96-3

20120831-142-I-75-05(6)

Jiangxi Synergy Pharmaceutical Co., Ltd

USP

2-[1-(aminomethyl)cyclohexyl]acetic acid

1-(Aminomethyl)cyclohexaneacetic acid

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ( GABA ) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism making it unlikely to participate in pharmacokinetic drug interactions. It is structurally and functionally related to another GABA derivative, pregabalin .

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