
原料药
Gabapentin
KDMF APIs
Gabapentin
韩文名称 | 가바펜틴 |
|---|---|
分类 | 中枢神经系统药物 |
CAS No. | 60142-96-3 |
KDMF 登记号 | 20120831-142-I-75-05(6) |
生产厂商 | Jiangxi Synergy Pharmaceutical Co., Ltd |
规格 | USP |
品目信息
IUPAC Name | 2-[1-(aminomethyl)cyclohexyl]acetic acid |
|---|---|
Synonyms | 1-(Aminomethyl)cyclohexaneacetic acid |
Description | Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ( GABA ) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages as compared with other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and lack of appreciable metabolism making it unlikely to participate in pharmacokinetic drug interactions. It is structurally and functionally related to another GABA derivative, pregabalin . |
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