KO

원료의약품

Dexibuprofen D.C. (덱시부프로펜디.씨.)

KDMF APIs

Dexibuprofen D.C.

Dexibuprofen D.C. 기본 정보

품목명 (한글)

덱시부프로펜디.씨.

분류

중추신경계

CAS No.

51146-56-6

KDMF 등록번호

20120406-145-I-37-02(3)

제조원

Hubei Biocause Heilen Pharmaceutical

규격

KP

품목 정보

Dexibuprofen D.C. 품목 정보

IUPAC Name

(2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid

Synonyms

(+)-(S)-p-isobutylhydratropic acid (2S)-2-(4-isobutylphenyl)propanoic acid (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid d-ibuproten Dexibuprofeno

Description

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability 4. For Metabolism, Enzymes, Carriers, Transporters Sections, refer to Ibuprofen.

Certificate of Analysis

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