原料药
Dexibuprofen D.C.
KDMF APIs
Dexibuprofen D.C.
韩文名称 | 덱시부프로펜디.씨. |
|---|---|
分类 | 中枢神经系统药物 |
CAS No. | 51146-56-6 |
KDMF 登记号 | 20120406-145-I-37-02(3) |
生产厂商 | Hubei Biocause Heilen Pharmaceutical |
规格 | KP |
品目信息
IUPAC Name | (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid |
|---|---|
Synonyms | (+)-(S)-p-isobutylhydratropic acid (2S)-2-(4-isobutylphenyl)propanoic acid (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid d-ibuproten Dexibuprofeno |
Description | Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability 4. For Metabolism, Enzymes, Carriers, Transporters Sections, refer to Ibuprofen. |
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