Cimetidine
시메티딘
KDMF APIs소화기관KDMF 등록
품목명 (영문)
Cimetidine
품목명 (한글)
시메티딘
분류
소화기관
CAS No.
51481-61-9
KDMF 등록번호
20060302-27-B-229-04(3)
제조원
Union quimico farmaceutica, S.A
규격
USP
IUPAC Name
(Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
Synonyms
1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine
2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine
Description
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Certificate of Analysis
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