원료의약품
Choline Fenofibrate (페노피브레이트콜린)
KDMF APIs
Choline Fenofibrate
품목명 (한글) | 페노피브레이트콜린 |
|---|---|
분류 | 중추신경계 |
CAS No. | 856676-23-8 |
KDMF 등록번호 | 20180814-209-J-48(3) |
제조원 | Alembic Pharmaceuticals Limited(API Unit-1) |
규격 | In-house |
품목 정보
Synonyms | Fenofibric acid choline salt |
|---|---|
Description | Fenofibrate is a third generation fibric acid derivative that is predominantly administered as monotherapy to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B and alternatively to increase high-density lipoprotein cholesterol in patients diagnosed with primary hyperlipidemia or mixed dyslipidemia and to reduce triglycerides in patients with severe hypertriglyceridemia. Fenofibrate however is generally extremely lipophilic, largely insoluble in water, and poorly absorbed 1 . As the primary active metabolite of fenofibrate however, various hydrophilic salt formulations of fenofibric acid have since been developed, resulting in therapeutic agents that demonstrate far greater solubility, absorption throughout the gastrointestinal tract, bioavailability, and capability to be administered irrespective of patient food intake |
Certificate of Analysis | If you need more information, please contact us. |
규격서·시험성적서 등 추가 자료가 필요하시면 문의 시 함께 요청해 주세요. 담당자가 확인 후 회신드립니다. (02-579-1056 · ace@acebiopharm.com)