Choline Fenofibrate

Choline Fenofibrate

페노피브레이트콜린

중추신경계

856676-23-8

20180814-209-J-48(3)

Alembic Pharmaceuticals Limited(API Unit-1)

In-house

Fenofibric acid choline salt

Fenofibrate is a third generation fibric acid derivative that is predominantly administered as monotherapy to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B and alternatively to increase high-density lipoprotein cholesterol in patients diagnosed with primary hyperlipidemia or mixed dyslipidemia and to reduce triglycerides in patients with severe hypertriglyceridemia. Fenofibrate however is generally extremely lipophilic, largely insoluble in water, and poorly absorbed 1 . As the primary active metabolite of fenofibrate however, various hydrophilic salt formulations of fenofibric acid have since been developed, resulting in therapeutic agents that demonstrate far greater solubility, absorption throughout the gastrointestinal tract, bioavailability, and capability to be administered irrespective of patient food intake

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