原料药
Terbinafine Hydrochloride
KDMF APIs
Terbinafine Hydrochloride
韩文名称 | 테르비나핀염산염 |
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分类 | 皮肤用药 |
CAS No. | 91161-71-6 |
KDMF 登记号 | 20190322-49-A-349-21 20050905-49-A-94-10(11) |
生产厂商 | Zhejiang East-Asia Pharmaceutical Co., Ltd. |
规格 | EP |
品目信息
IUPAC Name | [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine |
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Synonyms | (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine |
Description | Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway. Terbinafine hydrochloride was granted FDA approval on 30 December 1992. |
Certificate of Analysis | If you need more information, please contact us. |
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