原料药
Levofloxacin hydrate
KDMF APIs
Levofloxacin hydrate
韩文名称 | 레보플록사신수화물 |
|---|---|
分类 | 化疗药物 |
CAS No. | 1381997-71-0 |
KDMF 登记号 | 20100414-102-F-50-10(10) |
生产厂商 | Zhejiang East-Asia Pharmaceutical Co., Ltd. |
规格 | USP |
品目信息
IUPAC Name | bis((2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0⁵,¹³]trideca-5(13),6,8,11-tetraene-11-carboxylic acid) hydrate |
|---|---|
Synonyms | L-ofloxacin / Levofloxacin / Levofloxacin (as hemihydrate) / Levofloxacin hydrate / Ofloxacin S-(-)-form hemihydrate |
Description | Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racem ic ofloxacin . It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin 1 and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones such as gatifloxacin and moxifloxacin , is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in respiratory infections. Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and se veral South American countries soon after. 1 |
Certificate of Analysis | If you need more information, please contact us. |
如需规格书 · 检验成绩书等附加资料，请在咨询时一并提出。负责人确认后将回复您。（02-579-1056 · ace@acebiopharm.com）