Topiramate

토피라메이트

KDMF APIs중추신경계KDMF 등록
품목명 (영문)
Topiramate
품목명 (한글)
토피라메이트
분류
중추신경계
CAS No.
97240-79-4
KDMF 등록번호
20130912-170-I-365-10(2) 20160713-170-I-472-16(1)
제조원
Bal Pharma Limited Nifty Labs Pvt.,Ltd.
규격
USP
IUPAC Name
[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0²,⁶]dodecan-6-yl]methyl sulfamate
Synonyms
2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate
Description
Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. Since 2012, the extended-release formulation has been approved in combination with   phentermine   for chronic weight management therapy in adults. Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug
Certificate of Analysis
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