Roxithromycin
록시트로마이신
KDMF APIs항생물질제제KDMF 등록
품목명 (영문)
Roxithromycin
품목명 (한글)
록시트로마이신
분류
항생물질제제
CAS No.
80214-83-1
KDMF 등록번호
20050831-9-A-2-02(12)
제조원
Zhejiang Zhenyuan Pharmaceutical Co. Ltd.
규격
EP/In-house
IUPAC Name
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one
Synonyms
(9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)
Description
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin . It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila . Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections.
Certificate of Analysis
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