KO

원료의약품

Losartan Potassium (로사르탄칼륨)

KDMF APIs

Losartan Potassium

Losartan Potassium 기본 정보

품목명 (한글)

로사르탄칼륨

분류

순환계

CAS No.

124750-99-8

KDMF 등록번호

20100226-122-G-47-16(2) / 20100226-122-G-72-17(7) / 20100616-122-G-60-22(12)

제조원

IPCA Laboratories Limited / Zhejiang Huahai Pharmacetical Co., Ltd / Zhejiang Tianyu Pharmaceutical Co., Ltd

규격

USP

품목 정보

Losartan Potassium 품목 정보

IUPAC Name

potassium 5-[2-(4-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)phenyl]-1,2,3,4-tetrazol-2-uide

Description

Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo or hydrochlorothiazide . Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. Patients taking losartan should have their renal function and potassium levels monitored. Losartan was granted FDA approval on 14 April 1995.

Certificate of Analysis

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