Dexibuprofen

Dexibuprofen

덱시부프로펜

중추신경계

51146-56-6

20120330-145-I-36-01(5) / 20130208-145-I-184-04(16)

Hubei Biocause Heilen Pharmaceutical Solara Active Pharma Sciences Limited

In-house

(2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid

(+)-(S)-p-isobutylhydratropic acid (2S)-2-(4-isobutylphenyl)propanoic acid (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid d-ibuproten

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability. For Metabolism, Enzymes, Carriers, Transporters Sections, refer to Ibuprofen.

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