원료의약품
Dexibuprofen (덱시부프로펜)
KDMF APIs
Dexibuprofen
품목명 (한글) | 덱시부프로펜 |
|---|---|
분류 | 중추신경계 |
CAS No. | 51146-56-6 |
KDMF 등록번호 | 20120330-145-I-36-01(5) / 20130208-145-I-184-04(16) |
제조원 | Hubei Biocause Heilen Pharmaceutical Solara Active Pharma Sciences Limited |
규격 | In-house |
품목 정보
IUPAC Name | (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid |
|---|---|
Synonyms | (+)-(S)-p-isobutylhydratropic acid (2S)-2-(4-isobutylphenyl)propanoic acid (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid d-ibuproten |
Description | Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability. For Metabolism, Enzymes, Carriers, Transporters Sections, refer to Ibuprofen. |
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