CN

原料药

Formoterol Fumarate

KDMF APIs

Formoterol Fumarate

Formoterol Fumarate 基本信息

韩文名称

포르모테롤푸마르산염

分类

呼吸系统

CAS No.

43229-80-7

KDMF 登记号

20111202-187-I-22-11

生产厂商

Mylan Laboratories Limited (Unit-11)

规格

EP

品目信息

Formoterol Fumarate 品目信息

IUPAC Name

N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide

Synonyms

2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilide, Formoterol

Description

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers. A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as salbutamol, combined with a long duration of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication. It is available as a single-entity product and in several formulations in combination with both inhaled corticosteroids and long-acting muscarinic antagonists.

Certificate of Analysis

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