API
Clobetasol Propionate
KDMF APIs
Clobetasol Propionate
Korean name | 클로베타솔프로피오네이트 |
|---|---|
Category | Integument |
CAS No. | 25122-46-7 |
KDMF registration No. | 20170516-93-E-131-08 |
Manufacturer | Symbiotica Speciality Ingredients Sdn. Bhd |
Specification | USP |
Product information
IUPAC Name | (1R,2S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl propanoate |
|---|---|
Synonyms | 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate |
Description | Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985. |
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